WSSFN – World Society for Stereotactic and Functional Neurosurgery
WSSFN – World Society for Stereotactic and Functional Neurosurgery
Speakers
Jin Woo Chang, MD, PhD
Jin Woo Chang, MD, PhD
WSSFN President
> Opening remarks
Currently Dr. Chang serves as president of World Society for Stereotactic & Functional Neurosurgery (WSSFN) from 2019. In addition, he is also a section editor of World Neurosurgery and member of the editorial board for the official journal of WSSFN as well as the official journal of the International Neuromodulation Society (INS). Current position: Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
Kendall H. Lee, MD, PhD
Kendall H. Lee, MD, PhD
WSSFN Scientific Committee Chairman
> Welcome
Kendall H Lee is Professor of Neurological Surgery and Biomedical Engineering at Mayo Clinic Rochester. He received his M.D. and Ph.D. degrees from Yale University in 1998. His doctoral dissertation was on neurochemical modulation of synchronized oscillations in the thalamus (Department of Neurobiology). He completed his neurosurgery residency at Dartmouth-Hitchcock Medical Center, with an emphasis on stereotactic and functional neurosurgery and deep brain stimulation (DBS). In 2006, He joined Mayo Clinic as a stereotactic and functional neurosurgeon with clinical emphasis on DBS. He founded and is a co-director of the Mayo Neural Engineering Laboratories (NEL) since 2006. His research focusses on neuroscience, specifically in electrophysiology, stereotactic and functional neurosurgery, and electrochemistry. For the past fifteen years, his research has focused on elucidating the therapeutic mechanisms of electrical stimulation in restoring function in both brain and spinal cord. His lab’s endeavors have included intensive collaboration with Mayo’s Division of Engineering to develop novel research devices such as wireless fast-scan cyclic voltammetry designed for use during human and animal DBS surgery to monitor the neurochemical and electrophysiological bases of DBS, as well as research tools and novel stereotactic headframes and MR imaging strategies to investigate effects.
Nader Pouratian, MD, PhD
Nader Pouratian, MD, PhD
> Feasibility and Functional Outcomes of Human Visual Cortical Prostheses
Dr Pouratian’s integrated clinical and research interests focus on using and developing novel neuromodulatory approaches to ameliorate neurological and psychiatric disease. His research specifically focuses on in-depth exploration of brain mapping signals (LFP, ECoG, DTI, fMRI) in order to characterize the network basis of disease and therapeutic neuromodulation, with a goal of creating novel stimulation-based therapies.
Christian Lüscher, MD
Christian Lüscher ,MD
> Optical methods to observe and manipulate brain function
Christian Lüscher did his medical school in Lausanne & Berne. Since 2000 he is the head a research group and clinical attending at the Medical Faculty of the University of Geneva. His work aims at understanding the neural mechanism underlying addiction and other behavioral diseases, for which he has received numerous distinctions (e.g. Otto Naegeli Prize 2020). Recently, he has proposed novel protocols for deep brain stimulation based on optogenetic circuit interrogation in rodent models of addiction and obsessive compulsive disorders.
Michael Kaplitt, MD, PhD
Michael Kaplitt, MD, PhD
> Gene and Cell Therapy in Parkinson’s Disease
Michael G. Kaplitt, MD PhD is Professor of Neurological Surgery with tenure, Residency Program Director and Vice-Chairman for Research in the Department of Neurological Surgery at Weill Cornell Medical College-New York Presbyterian Hospital. He is also an Adjunct Faculty at The Rockefeller University and in the Department of Biomedical Engineering of Cornell University. He graduated Magna Cum Lauda in Molecular Biology and also received a Certificate of Proficiency in Russian Studies Princeton University. He then completed a PhD in Molecular Neurobiology at The Rockefeller University in 1993 and an MD from Cornell University Medical College in 1995. After his neurosurgery residency at the New York Presbyterian Hospital, he completed a fellowship in Stereotactic and Functional Neurosurgery at the University of Toronto. He is an internationally known expert in gene therapy and functional neurosurgery. In 1994, he described the first use of adeno-associated virus (AAV) in the mammalian brain and in 2003 he performed the first human gene therapy procedure for Parkinson’s disease which led to the first randomized, blinded study to show success for a CNS gene therapy. He has also been a lead or key investigator in several other gene therapy trials and studies of neurological devices for degenerative disorders. He has also become a leader in application of non-invasive MR guided focused ultrasound to the brain, including both lesioning of brain targets to improve movement disorders and disruption of the blood-brain barrier to allow non-invasive, focal delivery of biological agents to brain targets affected by neurological disease without surgery. His laboratory continues to focus upon use of both gene therapies and ultrasound technologies to better understand and potentially address unmet needs in Parkinson’s disease, memory and psychiatric disorders and brain tumors. He is an elected member of the American Society for Clinical Investigation and the Society for Neurological Surgeons, among other honors and awards.
Alex Green, FRCS(SN), MD
Alex Green, FRCS(SN), MD
> Effects of DBS on Sleep and Arousal and potential new therapies
Alexander L Green is a Neurosurgeon and the Spalding Associate Professor at the University of Oxford. His research focusses on autonomic neuromodulation and more recently, sleep and arousal. He has over 220 peer-reviewed publications and has received a number of prizes including the Congress of Neurological Surgeons (CNS) ‘Stereotactic and Functional Neurosurgery Resident Award’, the ‘Gordon Holmes Prize’ (Royal Society of Medicine), and the International Neuromodulation Society (INS) ‘New Investigator Award’
Jocelyne Bloch, MD
Jocelyne Bloch, MD
> NEUROTECHNOLOGIES RESTORING MOTOR CONTROL AFTER PARALYSIS
Jocelyne Bloch specialized in stereotactic and functional neurosurgery, and acquired an extensive experience in deep brain stimulation (DBS) and neuromodulation for movement disorders, pain and epilepsy. She is in charge of the functional neurosurgical unit at the CHUV. Very active in experimental medicine and translational neuroscience, she nourishes a profound interest in the development of new indications for DBS, and in advancing technologies and therapeutic paradigms in neuromodulation, neuroregeneration, and cell therapy. She seeks to gather all these novel therapeutic strategies under a common umbrella that will foster optimization of treatment options for patients suffering from neurological impairments. Since 2019, she is director of the Defitech Center for Interventional Neurotherapies (NeuroRestore). NeuroRestore is a research, innovation and treatment center that develops and applies bioengineering strategies involving neurosurgical interventions to restore neurological functions.
Moderated by
Kendall H. Lee, MD, PhD
Kendall H. Lee, MD, PhD
WSSFN Scientific Committee Chairman
Kendall H Lee is Professor of Neurological Surgery and Biomedical Engineering at Mayo Clinic Rochester. He received his M.D. and Ph.D. degrees from Yale University in 1998. His doctoral dissertation was on neurochemical modulation of synchronized oscillations in the thalamus (Department of Neurobiology). He completed his neurosurgery residency at Dartmouth-Hitchcock Medical Center, with an emphasis on stereotactic and functional neurosurgery and deep brain stimulation (DBS). In 2006, He joined Mayo Clinic as a stereotactic and functional neurosurgeon with clinical emphasis on DBS. He founded and is a co-director of the Mayo Neural Engineering Laboratories (NEL) since 2006. His research focusses on neuroscience, specifically in electrophysiology, stereotactic and functional neurosurgery, and electrochemistry. For the past fifteen years, his research has focused on elucidating the therapeutic mechanisms of electrical stimulation in restoring function in both brain and spinal cord. His lab’s endeavors have included intensive collaboration with Mayo’s Division of Engineering to develop novel research devices such as wireless fast-scan cyclic voltammetry designed for use during human and animal DBS surgery to monitor the neurochemical and electrophysiological bases of DBS, as well as research tools and novel stereotactic headframes and MR imaging strategies to investigate effects.
Mojgan Hodaie, MD FRCSC
Mojgan Hodaie, MD FRCSC
Dr. Hodaie is currently Professor of Surgery, University of Toronto and attending neurosurgeon at Toronto Western Hospital, University Health Network. Her research field focuses on the use of structural and advanced methods of imaging of brain white and gray matter in functional neurosurgery disorders including trigeminal neuralgia and chronic neuropathic pain. She currently serves as the vice-secretary of the World Society for Stereotactic and Functional Neurosurgery and has served as Chair of the Scientific Program for the WSSFN meetings in Mumbai (2015) and Berlin (2017).
Paresh Doshi, M.S., M.Ch
Paresh Doshi, M.S., M.Ch
Group Advisor, Functional Neurosurgery, Apollo Group of Hospital, India Positions:
- President The Neuromodulation Society
- Past President ISSFN
- Board member: INS, WSSFN, AASSFN
- Member: International task force for Psychiatric disorders
Recipient of the first Medscape India award for excellence in neurosciences
Recipient of Pharma Leaders Power Brand award-Excellence in Neurosciences, 2019
40 publications and 300 invited lectures.